Frequently Asked Questions FAQ - Technical Information

What is Lanomax?

Lanomax is a cataract dissolving eye drop for pets and other animals. Lanomax uses an innovative drug delivery system built using the latest advanced nanotechnology, called ThruDelivery™, to deliver lanosterol molecules into the crystalline lens of the eye without an injection. This system separates the lanosterol molecules from the carriers in the carrier-lanosterol complex attached to the corneal surface, and then quickly passes them through the cornea, anterior, iris and pupil to deliver them into the crystalline lens. It is because of this ThruDelivery™ system that Lanomax is the only eye drop on the planet to show a real therapeutic effect on cataracts.

What are the therapeutic effects of Lanomax?

Lanomax has an excellent therapeutic effect on incipient, immature, and mature cataracts. However, the therapeutic effect of Lanomax varies greatly depending on the type of cataract and the degree of progression of the cataract. Generally, in the case of incipient, immature, and mature cataracts, if you administer two vials of Lanomax eye drops to one eye for six weeks, you will see visible improvements when compared to the untreated eye. Sometimes there are dramatic cases where a visible effect can even be noticed within a short period of 1-2 weeks after beginning to administer Lanomax. Read reviews from customers who have had such dramatic experiences here.

Recently, similar eye drops mimicking the ingredients of Lanomax have been sold on Amazon and eBay. Do these lanosterol eye drops have the same cataract treatment effect as Lanomax?

No, not at all. Those imitation drops are simply aqueous solutions of lanosterol, in which lanosterol is dissolved in liposomes, nanoparticles, dextrin carriers, or oils. If you want to use these imitation drops to treat cataracts as well as Lanomax does, you will have to anesthetize your pet as described in the 2015 Nature paper and inject the solution directly into the vitreous body of the eyes with a syringe. These imitation drops will not show any cataract treatment effects when used without the injections. Moreover, injection therapy requires taking great risks, including the potential for bacterial or viral infections introduced during the injection and possible unexpected side effects that may occur when auxiliary ingredients other than lanosterol are introduced into the vitreous.

What types of cataracts can be treated with Lanomax?

In general, cataracts fall into four categories: age-related, congenital, secondary, and traumatic. In addition, cataracts are further categorized as cortical, nuclear, or posterior subcapsular, depending on the location of their outbreak. The causes and types of cataracts vary widely, but the biochemical mechanisms underlying cataracts are similar. At the molecular level, protein aggregation is a common cause of all cataracts. Lanomax effectively removes that protein aggregation. So, while Lanomax is effective for all types of cataracts, it takes the most time to treat posterior subcapsular cataracts where protein aggregation occurs at the furthest position from the cornea. This is because in posterior subcapsular cataracts lanosterol molecules must confront the most barriers to reach the protein aggregation.

Can brown cataracts be treated?

Nuclear cataracts change the nucleus in the center of the lens to yellow or brown. Lanomax has been shown to have a therapeutic effect on nuclear cataracts.

Can Lanomax be used for animals such as birds, minks or horses?

Lanomax can be used for cataracts that occur in all kinds of animals.

Can I use Lanomax for animals with diabetes?

Lanomax is safe for use on animals with age-related diseases, including diabetes.

Can Lanomax be used on animals with glaucoma? Does it increase the intraocular pressure?

Lanomax is safe for use on animals with glaucoma; it will not affect the intraocular pressure. However, it is unlikely to provide dramatic treatment effects in a short time if the cataract is in a hyper-mature state.

Are there any side effects when using Lanomax?

No. Lanomax eye drops are safe for both animals and humans. Lanosterol, the active ingredient of Lanomax, is a natural compound which is naturally occurring in the body tissue and blood of both animals and humans. It is already present in the crystalline eye lens as this compound is what helps the lens to maintain its transparency. Therefore, it does not cause any side effects for either animals or humans. Lanosterol, the active ingredient in Lanomax is naturally-sourced through extraction from sheep’s wool with 99.9% purity. In the tens of thousands of animals that have been treated with Lanomax to date, there has been exactly one report of any side effect at all. However, upon investigation, it was found that the side effects were caused by a lack of maintenance of the eye drops by the user, which caused the tip of the bottle to be exposed to an infection which was then passed to the eye. Providing you follow safe handling procedures to prevent contamination of the vial, there is no need to worry about any ill effects.

Does Lanomax include preservatives?

Lanomax does not contain any preservatives. This means that, if necessary, it is perfectly safe to increase use beyond the recommended dose (3 times a day, 1-2 drops each time). However, if the vial becomes contaminated with bacteria, it must be discarded immediately as it contains no preservatives. When administering Lanomax to the animal's eyes, do not touch the tip of container to the eye or any surface to avoid contamination. Once the Lanomax vial has been opened, you need to keep it refrigerated to prevent bacterial growth.

Does Lanomax contain PBS or Phosphate?

Until February 2017, Lanomax was produced using Phosphate and PBS (phosphate-buffered saline) as inactive ingredients. However, Lanomax produced on or after March 1, 2017 contains neither of these ingredients. We currently only produce and sell one kind of Lanomax, which does not contain either of those ingredients. Phosphate and PBS were inactive ingredients of Lanomax, so removing them from the formula in no way affected Lanomax’s cataract-removing effects.

Can Lanomax be used along with other eye drops?

Lanomax can disturb the absorption of other eye drops because of its high viscosity that allows it to coat the surface of the cornea for a certain period of time after applying. Other drops may have other effects that could impede the therapeutic effects of Lanomax. Therefore, avoid using Lanomax at the same time as other eye drops unless it is unavoidable. If you must use other eye drops along with Lanomax, please apply the drops at least 3 hours apart, administering each eye drop separately.

Is the application of Lanomax painful to animals?

No, there is no pain at all when using Lanomax. It is just like using artificial tears.

Do I need a prescription and veterinarian involved to use Lanomax?

No. Lanomax does not require consulting a veterinarian or getting a prescription.

How many times a day will I use Lanomax?

To treat one eye of a 20-kg dog, the standard minimum dosage is one to two drops three times each day. However, it is acceptable, and possibly beneficial, to exceed that dosage amount. If you need to treat a larger dog, an eye with more severe cataracts, or if you want to see faster treatment effects, you may need to use more drops more frequently than the standard dosage. As Lanomax does not contain any preservatives it is perfectly safe to increase the dose; there is no dose limit.

How long will one vial of Lanomax last?

If you treat one eye of your dog using the standard dosage of one or two drops three times each day, one vial of Lanomax will last for about 3 weeks.

What is the shelf-life of Lanomax?

Lanomax vials remain usable for up to 30 days after being opened. As Lanomax contains no preservatives, it is important to follow safe handling procedures. Do not allow the tip of the dropper to touch your animal’s lashes or skin, and make sure the vial is kept refrigerated. Unopened Lanomax vials may be stored at room temperature for 12 months from the date of manufacture.

Is Lanomax available in a larger size than 5ml?

As Lanomax contains no preservatives, it is vulnerable to the risk of bacterial infection. The small container size minimizes this risk by ensuring that the vial will be emptied in a shorter period of time. 5ml is the maximum allowable volume of eye drops with no preservatives for safe use.

Is it a problem if Lanomax is exposed to high temperatures during its delivery?

Unopened Lanomax vials may be stored at room temperature for 12 months from the date of manufacture. In addition, the Lanomax eye drop solution is very stable and thus is not affected by temporary exposure to high temperatures. However, the container holding the drops has a lower heat resistance, so avoid exposing it to very high temperatures over 90°C.

It is very sticky when you touch the substance with your hands. Why?

The reason for the high viscosity of Lanomax eye drops is due to the compound hydroxypropyl-ß-cyclodextrin (HPßCD), which is used to maintain long-term adherence without flowing away from the corneal surface. This compound has a large molecular weight and cannot pass through the cornea, so it remains on the surface of the eye and is eventually naturally flushed out by the eye, sometimes creating tangles in the animal's fur. When cleaning the fur around the animal's eye, please do not use combs. Instead, wash gently with water.

During the use of Lanomax, the cataracts split into multiple fragments. What causes this?

It is a desirable phenomenon to see the protein aggregation (the cause of cataract) is dissolving. This is nothing to be alarmed about and you should continue the treatment.

I am using the second bottle of Lanomax, but the second bottle seems to be less effective than the first. Why?

This can happen when cataracts occur in two or more locations. For example, when cortical cataracts and posterior subcapsular cataracts occur simultaneously, the therapeutic effect of Lanomax will first appear in the cortical cortex which is near to the cornea. However, because the posterior subcapsular cataract is relatively farther away from the cornea than the cortex, a smaller amount of lanosterol molecules are reaching the location and it takes a longer period of time for the molecules to reach the area. Therefore, the treatment effect can be much slower, and give the appearance that the second bottle is less effective.

Will it cause any problems if the Lanomax treatment is stopped before the cataracts are completely cured?

Temporarily or permanently stopping treatment should cause no problems. You can restart treatment later if you choose.

Must I continue to use Lanomax after the cataracts are completely cured?

No. Once the cataracts are completely cured, there is no need to continue to use Lanomax. However, you may want to continue to use a low dose of Lanomax as a preventative measure against the recurrence of cataracts.

Can I inject Lanomax into the vitreous body of the eye for faster results?

No, you must not inject Lanomax into eyes. Lanomax contains various other ingredients besides lanosterol. Lanosterol is a natural component that is naturally occurring in the lens, but all the other components are foreign substances that should not be introduced to the lens. Injecting these components directly into the vitreous, could cause serious harm. Lanomax must be used only as eye drops.

Why Lanomax is so expensive compared to other eye drops?

Lanomax is not a simple lanosterol solution, but rather a lanosterol delivery system that is produced through a high-level nanotechnology process involving more than 24 steps. Therefore, the production cost is relatively higher than other eye drops produced by simple mixing. Moreover, the fact that we cannot produce Lanomax in large quantities due to limited demand is another reason for the high price. However, we expect that as the demand for Lanomax increases in the future, the price will be drastically lowered as it becomes possible to be produced in large quantities.

 

 

FAQ - Orders and Shipping

Is Lanomax available in my country?

Lanomax is currently available online in most countries through our official website.

How much does shipping cost?

Shipping fees vary by carrier and destination. To find the exact shipping fee, first go to this web page and click the ‘Add to Cart’ button. On the right side of the following web page, when you click ‘Estimate Shipping and Tax’ and enter your shipping address, accurate shipping charges will be automatically calculated for each carrier.

How long is the delivery time?

You can use the following links to determine the normal shipping times to your location:

USPS Domestic Shipping Services: https://www.usps.com/ship/mail-shipping-services.htm
USPS International Shipping Services: https://www.usps.com/international/mail-shipping-services.htm
UPS Domestic Shipping Services: https://www.ups.com/us/en/shipping/services/domestic.page
UPS International Shipping Services: https://www.ups.com/us/en/shipping/international/services.page

Will there be any problem with customs clearance when ordering Lanomax from overseas?

If you order Lanomax from overseas, you may experience problems in customs clearance, such as a delay in clearance or, in rare cases, no clearance. The main countries that have this problem are Germany, Australia, Italy, Brazil, South Africa and Mexico, where imports of Lanomax are restricted to doctors and/or companies that are permitted to import medicines. We have a ‘Discreet Shipping’ service for customers who are concerned about potential customs clearance issues.

What is the ‘Discreet Shipping’ service?

If you choose 'Discreet Shipping' when ordering Lanomax, you will receive vials containing Lanomax eye drops, but there will be no identifying stickers on the vials, no included product instructions, or any labeled product cases. In addition, the invoice will list the product name as 'Supplements for Dog Health' and the price of each item will be declared as $9.99. If you want fast and secure customs clearance in your country, please choose this special service.

How can I choose the ‘Discreet Shipping’ service?

When ordering Lanomax, you will be able to opt between ‘Standard Shipping’ and ‘Discreet Shipping’ when choosing your ‘Shipping Options’.

I am concerned about the cost of import duty. Can you lower the price of a commodity on a commercial invoice?

If you choose 'Discreet Shipping' when ordering Lanomax, we will declare the price as $9.99 per vial on the commercial invoice.

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